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The parents of terminally-ill baby Charlie Gard are 'utterly distraught' and facing fresh heartbreak after losing their final appeal in the European Court of Human Rights.

Chris Gard, 32, and Connie Yates, 31, wanted to take their 10-month-old son - who suffers from a rare genetic condition and has brain damage - to the US to undergo a therapy trial.

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Specialists in the US have offered a therapy called nucleoside.

During hearings in London, barrister Richard Gordon QC, who leads Charlie's parents' legal team, has given indications of the case the couple are mounting in the European court.

'Charlie's parents also asked the courts to consider whether it would be in the best interests of their son to undergo experimental treatment in the US.

'The domestic courts concluded that it would be lawful for the hospital to withdraw life sustaining treatment because it was likely that Charlie would suffer significant harm if his present suffering was prolonged without any realistic prospect of improvement, and the experimental therapy would be of no effective benefit.'The domestic court decisions had been meticulous, thorough and reviewed at three levels of jurisdiction with clear and extensive reasoning giving relevant and sufficient support for their conclusions; the domestic courts had direct contact with all those concerned.'The domestic courts had concluded, on the basis of extensive, high-quality expert evidence, that it was most likely Charlie was being exposed to continued pain, suffering and distress and that undergoing experimental treatment with no prospects of success would offer no benefit, and continue to cause him significant harm.'It comes after a High Court judge in April ruled against a trip to America and in favour of Great Ormond Street doctors.

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It comes after specialists at Great Ormond Street said therapy in the US is experimental and will not help and added that life support should stop.

And after losing legal battles in the UK, Charlie's parents were hoping judges in Strasbourg, France, would come to their aid.

He has suggested that British government ministers may be in breach of human rights obligations as a result of decisions by judges in London.

He has said parents should be free to make decisions about their children's treatment unless any proposal poses a risk of significant harm.

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